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The newspaper ads are part of an urgent, two-pronged attempt by GSK to pre-empt more negative publicity today, because now the issue has reached Capitol Hill, and Avandia and GSK are pitched into the political battle over the future of drug safety regulation in the US.

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Since then, FDA has continued to actively monitor adverse events associated with Rezulin, as well as Avandia and Actos.

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Included on Avandia labeling are the warnings that Avandia side effects can be as serious as cardiac events, including failure, and hepatic risks.

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